The Bible states that God originally planted the garden “eastward in Eden.” according to Genesis 2:8, implying that Eden was a larger geographic area than just the garden. After Cain murdered Abel, he “went out from the presence of the Lord and dwelt in the land of Nod on the east of Eden.” (4:16) So it must be observed that, technically, Adam and Eve still lived in Eden, though not in the garden, and had no access to the tree of life. God cast them out, expelled them, for their own good and the good of all mankind.
While they were in the garden of God, God provided all, but now, Adam had to till the ground and start from scratch, so to speak. Life would be different from then on and not just due to the increased workload. The Bible states in Genesis 3:21 that God made Adam and Eve coats of skins and clothed them. A blood sacrifice was made for their sin, and they were forgiven. There was still access to God. God did not abandon them. But the conditions and the rules had drastically changed. The dominion, power and authority that had been conferred upon Adam had been transferred to God's archenemy.
When the Devil tempted Jesus Christ, he could legally offer the kingdoms of the world. “All this authority I will give You, and their glory; for this has been delivered to me, and I give it to whomever I wish.&rdquo (Luke 4:6) Adam had delivered it to the Devil, and was no longer enjoying the role of “prince of this world,” a title now belonging to the adversary. (John 12:31 and 14:30) The one called the serpent in Genesis 3 is called the “god of this age” according to 2 Corinthians 4:4.
Adam and Eve lived long lives and had many children. They also had their share of grief. They lost their first two sons, one murdered by the other, and Cain left their presence and was likely not seen again. However, God made a promise to Adam and Eve, and through one of their descendents (Seth) would come the One who would bruise the head of the serpent, the Promised Seed, Jesus Christ.